Syncapone is an oral tablet that is prescribed to Parkinson’s patients. It intends to minimize excessive shaking by slowing down body movements. It is a highly effective medicine for Parkinson’s disease. Syncapone works as a dopamine booster by increasing Dopamine levels in the brain. In a nutshell, it helps Parkinson’s patients to gain full control over movements & minimize abnormalities in movements.
Let’s have a look at the active ingredients of Syncapone, i.e., Levodopa + Carbidopa + Entacapone in Parkinson’s disease.
Levodopa is a recognized drug for Parkinson’s disease. It manages Parkinson’s motor symptoms like some popular dopamine agonists & MAO-B inhibitors. Secondly, Carbidopa inhibits the peripheral metabolism of Levodopa. It means that Carbidopa functions allow Levodopa to maintain its effectiveness in the Central Nervous System by not letting any blood-brain barrier form. Lastly, Entacapone consistently boosts Levodopa levels & supports the working of Carbidopa. This lets Levodopa prevent Parkinson’s symptoms like tremors; muscular stiffness, poor muscular control, etc stay away.
|USA Brand Name||Generic Name||Legal Status||Drug Class||Prescription Required|
|Stalevo||Carbidopa, Levodopa, Entacapone||USA, India & Europe||Dopamine Precursor||Yes|
Uses of Syncapone
Syncapone is mostly prescribed to Parkinson’s patients. However, it may be prescribed to people suffering from Restless Leg Syndrome sometimes, if the condition permits.
Why use Syncapone?
Syncapone benefits in minimizing the symptoms of Parkinson’s disease. Its active ingredients – Levodopa + Carbidopa + Entacapone in Parkinson’s disease are working in combination for boosting & maintaining dopamine levels in the brain. Thus, regular movements are controlled well, Parkinson’s symptoms are minimized & the patient feels normal.
How to use Syncapone?
Syncapone is available as an oral tablet form. It should only be used as per the doctor’s prescription & guidance. This medicine is taken orally with a glass of water. You should swallow it as a whole & not crush, break, or chew it in any case. Syncapone can be used with or without food.
Avoid alcohol or grapefruit juice consumption while you’re undergoing treatment with Syncapone as it may show negative effects with its active ingredients. Please take the prescribed dosage of Syncapone at the same time daily. Don’t overdose it else severe adverse effects may be observed instantly.
Note: Syncapone dosage should not be increased or decreased based on self-assumptions. If you have any queries, kindly visit your doctor & find your answers instead of harming yourself with unnecessary changes to the dosage.
How Syncapone work?
Syncapone, also popularly known as a combination of Levodopa + Carbidopa + Entacapone in Parkinson’s disease, has a simple working mechanism. Its effectiveness is based on the individual ingredient’s effectiveness which is as follows:
- Levodopa works as a dopamine booster. It improves the working of dopamine in the brain which, in turn, improves movement control happening from the brain.
- Carbidopa acts as a supporter of Levodopa. It prevents Levodopa breakdown before it reaches the brain. This helps Levodopa to work efficiently & with the least side effects.
- Entacapone is here as another dopamine enhancer that increases dopamine levels for controlling & maintaining regular body movements.
Thus, the combination of Levodopa + Carbidopa + Entacapone works for improving body movements in Parkinson’s disease.
Side Effects of Syncapone
- Memory changes
- Decreased appetite & weight
- Joint pain & weakness
- Muscular pain
- Chest pain
- Vision changes
- Discoloration of urine
- Upset stomach
- Shortness of breath
- Irregular heartbeat
- Uncontrollable movements or imbalance
- Cardiac arrest
- Itching sensations
- Colon inflammation
- Increased sexual desires
- Abnormal liver functions
- Trouble in swallowing
- Difficulty in urination
- Eating more frequently
- Uncontrolled mood swings
- Skin, nail, hair, or sweat discoloration
- The rigidity of muscles & movements
- Suddenly increased heartbeat
- Blood pressure fluctuations
- Allergic reactions with throat, skin, lips, etc.
- Take the prescribed dosage of Syncapone only. Don’t adjust the dosage by increasing or decreasing it based on self-assumptions
- Don’t take Syncapone endlessly. Visit your doctor at frequent intervals, track the progress & ask him for how long you have to continue using Syncapone.
- Please don’t stop taking Syncapone whenever you wish. Ask your doctor to safely discontinue Syncapone so that no severe adverse effects are observed.
Warnings & Precautions
- Discuss with your doctor if you’re allergic to active ingredients of dopamine supplements like Levodopa + Carbidopa + Entacapone in Parkinson’s disease.
- Your doctor should know if you have any major health problems like heart, kidney, liver, eye, adrenal gland tremor, malignant syndrome, muscular disorders, etc.
- Tell your doctor if you have had heart surgery in the past or planning to have one anytime soon.
- Don’t forget to tell your doctor about ulcers or convulsions, if ever faced before.
- Your doctor should know if you’re planning to conceive so that they can decide whether or not to prescribe Syncapone.
- Stay away from alcohol consumption for the duration you’re undergoing treatment with Syncapone. It will help you stay away from excessive dizziness or instant allergic reactions.
When to NOT use Syncapone?
- Please don’t use Syncapone without a prescription for adults.
- Syncapone is not for the use of children under 18 years of age.
- Pregnant or breastfeeding women should tell their present situation to the doctor before Syncapone is being prescribed to them.
- Avoid using Syncapone if you’re seeing side effects that are lasting longer than usual or showing any severe negative impacts.
It’s important to know the interactions of Syncapone with other drugs or medicines. You should talk to your doctor if you’re taking any medicines already or have allergies to certain ingredients.
Here are the conflicting medicines with Syncapone:
- Iron Supplements
- Respiratory disease medicines like Rimiterole & Isoprenaline
- Parkinson’s medicine like Apomorphine
- Dopamine antagonists
Note: This is not a complete list of conflicting medicines with Syncapone. There could be more.
Syncapone is to be stored at normal room temperature: 15 to 30 Degrees Celsius.
1) Is Syncapone Safe?
Syncapone is safe to use for as long as you are using Syncapone as per the doctor’s prescription. If you’re seeing any side effects frequently or observing severe negative impacts then you should talk to your doctor.
2) How long does Syncapone Take to Get into Effect?
Consider the effective duration of Syncapone after 1 hour of its consumption.
3) For How Long does the Effect of Syncapone Last?
It isn’t clinically proven as to how long the effectiveness of Syncapone lasts in the human body.
4) Is Alcohol Consumption Safe During Syncapone Usage?
Neither alcohol nor grapefruit juice should be consumed near using Syncapone else excessive dizziness may happen.
5) Is Syncapone Habit-Forming?
Parkinson’s patients using Syncapone haven’t reported any habit-forming complaints to date.