Tegonat 15 (Tegafur/Gimeracil/Oteracil)

Tegonat 15 mg capsule is used for chemotherapy treatment in patients with advanced stomach cancer. Manufactured by Natco Pharma Ltd., this medicine is formulated for managing and treating stomach cancer while slowing down the progression of the disease.

What is Tegonat 15?

Tegonat 15 mg is a chemotherapy drug used orally for advanced stomach cancer treatment. It classifies as an antineoplastic agent that helps prevent the growth and spread of cancer cells. This medicine contains three active ingredients (Tegafur, Gimeracil, and Oteracil), precisely combined to enhance the overall effectiveness of the medicine.

How Does Tegonat 15 Work?

The working of Tegonat 15 mg depends on its active ingredients Tegafur/Gimeracil/Oteracil. Each of them plays a unique role in stomach cancer treatment explained as below:

Tegafur: It is a prodrug of 5-Fluorouracil (5-FU) which works by inhibiting DNA synthesis of cancer cells, thus slowing down their growth.

Gimeracil: This drug is used for enhancing effectiveness of Tegafur. It does so by preventing its breakdown for ensuring long-lasting anti-cancer effects.

Oteracil: Helps in reducing adverse effects of chemotherapy, mainly on the gastrointestinal tract, thus improving tolerance among patients.

All three ingredients work in combination to manage stomach cancer without causing any major side effects.

How to take Tegonat 15 mg?

Your healthcare provider will share appropriate guidance on how to take Tegonat 15 mg dosage correctly for optimal results.

• The capsule is typically swallowed at a fixed time regularly for the suggested treatment period.
• Swallow the capsule with a glass of water without breaking it open using its contents separately.
• It can be used with or without food.

Indications and Uses

Stomach cancer treatment (advanced level)

This chemotherapy drug may be prescribed alone or as a supportive therapy with other treatments.

What is the recommended dosage of Tegonat 15?

Tegonat 15 Dosage is recommended considering several factors like age and body weight of the patient, pre-existing medical conditions, ongoing treatments (if any), stage of cancer, etc. Hereby, the dosage varies among patients as per their medical requirements and response to the drug.

This medicine is however used in cycles (consumed for a specific period and paused for some time) for allowing body to recover from chemotherapy effects. The patient is supposed to follow the recommended dosage exactly and not exceed it in any circumstances for avoiding critical reactions.

Don’t make any alterations to the treatment plan or dosage frequency on your own. Seek medical help if you think you need a change.

Side Effects of Tegonat 15

Just like any other chemotherapy drug, some side effects are possible while using this medicine too. The common ones include:

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Loss of appetite
• Weakness
• Fatigue
• Mouth sores
• Low white blood cell count (increased risk of infections)

The patient might not require medical attention unless these symptoms get severe and intolerable or any major side effects show up:

• Symptoms of kidney or liver dysfunction
• Serious allergic reactions – swelling, shortness of breath, difficulties in swallowing, etc

Precautions

It is essential to follow some precautionary measures to ensure the safe usage of this medication. Here are a few things to consider during the treatment period:

• Read product label for full list of ingredients. Inform your physician if you are allergic to any of them, particularly Tegafur/Gimeracil/Oteracil.
• Don’t use this chemotherapy drug during pregnancy or breastfeeding. Also, avoid planning pregnancy while on treatment with this drug.
• Patients with pre-existing kidney or liver disorders are selectively prescribed this medicine, only if unavoidable. So, tell your doctor if you have any such health concerns.
• Your physician may recommend regular monitoring of blood cell count with blood tests. Conduct them duly.
• Have nutrition-rich foods and stay hydrated throughout the treatment period.
• Avoid drinking alcohol during the treatment phase because it can impair the performance of this drug.

Contraindications with Medical Conditions

Tegonat 15 mg capsules are not indicated among patients with any of these critical health issues pre-existing:

• Diabetes
• Blood cancer
• Bleeding disorder
• Liver impairment
• Persistent diarrhoea
• Blood thinning problems
• Skin discoloration

Interactions with Other Medications

These are the formerly known interacting drugs of Tegonat. Don’t use them together with this cancer treatment. Discuss with your doctor whether you can use them or not during the treatment period with this medicine.

• Warfarin
• Cisplatin
• Clobazam
• Carbamazepine
• Immunosuppressants
• Alternate chemotherapy medications
• Vitamins or herbal supplements

Dosage Alternatives

• Tegonat 20 mg

Conclusion

Tegonat 15 mg is a recognized chemotherapy drug, mainly used for stomach cancer treatment. Its potent combination of Tegafur/Gimeracil/Oteracil helps in slowing down the progression of cancer without any major gastrointestinal symptoms. It should however be used with caution, just like any other chemotherapy medication. Adhere to dosage guidelines shared by the physician. Follow the treatment plan & visit the doctor at regular intervals for adjustments and tracking improvements (if required).

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